Alpha-GPC

L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain. It is also a parasympathomimetic acetylcholine precursor which has been investigated for its potential for the treatment of Alzheimer’s disease and other dementias. Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines. Alpha-GPC rapidly delivers choline to the brain across the blood – brain barrier and is a biosynthetic precursor of acetylcholine. It is a non-prescription drug in most countries. The FDA determined that intake of no more than 196.2 mg / person / day is considered generally recognized as safe (GRAS).